Gerry McCann was reacting to news of an injunction against the further publication of a book called The Truth of the Lie by Goncalo Amaral, a former policeman who investigated the disappearance of the youngster.
In the book, Mr Amaral alleges Madeleine is dead and that her parents Kate and Gerry McCann were somehow involved in her disappearance.
Mr McCann, 41, said: "There's a lot of people in Portugal, who might have evidence, that believe Madeleine is dead.
"If people believe that they won't search for her and they won't come forward with information.
"I know for a fact people have been told Madeleine is dead. There is no evidence to support that and that is unforgivable."
Madeleine disappeared from her family's apartment during a holiday to the Portuguese resort of Praia da Luz in May 2007.
The decision by Lisbon's main civil court means that copies of the book which are still on sale have to be passed on to the McCanns' solicitors so that, if they choose, the books can be destroyed.
The decision to impose the injunction comes after a year-long campaign by the McCanns' lawyers to prevent the publication of the book and a subsequent DVD.
It also applies to a TV programme about Madeleine's disappearance which Mr Amaral produced several months ago, and the rights for a subsequent film.
Any money awarded by the courts as compensation would be ploughed back into the Find Madeleine Fund, which is paying private investigators to search for the youngster.
Mr Amaral previously worked on the investigation into the disappearance of the three-year-old but was removed from it after he criticised British police.
The injunction means he has to ensure all unsold copies of the book are removed from shops and warehouses across Europe or he faces a 1,000 euro-a-day (£877) fine.
It is understood that Mr Amaral has 30 days to appeal against the injunction. The McCanns insist that they only took legal action as a last resort, which they felt they had to launch as they tried to produce a fresh documentary earlier this year appealing for evidence in the search for their daughter while at the same time Mr Amaral was claiming that Madeleine was dead.
Mr McCann described Mr Amaral's book as a "skewed version of events".
He added: "This has been incredibly damaging. People have profited from the book. The question I would be asking is why someone would be continuing to purport a thesis that a child is dead when there is no evidence.
"As parents the search goes on and what I would ask is that if anyone has any information that might be relevant to come forward, please."
Earlier Mr McCann's family spokesman Clarence Mitchell said the couple were "absolutely delighted" by the granting of the injunction.
He said Mr Amaral's claim that he believed Madeleine was dead was threatening the search for the youngster.
The former detective also claimed he did not believe the McCanns' account that Madeleine was taken while they were eating with friends nearby.
The injunction bans Mr Amaral from repeating his claims about Madeleine or her parents. It also forces copyright for the book and the film to be passed to the McCanns' lawyers.
In a statement the McCanns, of Rothley, Leicestershire, said: "We are pleased with the judge's decision today preventing further distribution and sale of Mr Amaral's book and DVD - The Truth of The Lie.
"Mr Amaral's central thesis has no evidence whatsoever to support it to claim, as he did, that Madeleine is dead, and that we, as her parents, were in some way involved with her disappearance has caused our family incredible distress and continues to do so.
"Without doubt, Madeleine will have suffered as a result of the negative effect this book and DVD will have had on the search for her. Sean and Amelie need protection too, from such awful claims."
Twins Sean and Amelie, now four, are the couple's younger children who were also in the holiday apartment when Madeleine went missing.
The statement ended by saying: "Hopefully this injunction today will go a long way towards reducing further unnecessary and unjust distress to us all and allow people to concentrate completely on what is important - finding Madeleine."
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